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[[Image:2eua.jpg|left|200px]]


{{Structure
==Structure and Mechanism of MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia Coli==
|PDB= 2eua |SIZE=350|CAPTION= <scene name='initialview01'>2eua</scene>, resolution 2.500&Aring;
<StructureSection load='2eua' size='340' side='right'caption='[[2eua]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene>
<table><tr><td colspan='2'>[[2eua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EUA FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Isochorismate_synthase Isochorismate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.4.2 5.4.4.2] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
|GENE= menF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eua OCA], [https://pdbe.org/2eua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eua RCSB], [https://www.ebi.ac.uk/pdbsum/2eua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eua ProSAT]</span></td></tr>
|RELATEDENTRY=[[2euj|2EUJ]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eua OCA], [http://www.ebi.ac.uk/pdbsum/2eua PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2eua RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/MENF_ECOLI MENF_ECOLI]
 
== Evolutionary Conservation ==
'''Structure and Mechanism of MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia Coli'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/2eua_consurf.spt"</scriptWhenChecked>
2EUA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EUA OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eua ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Isochorismate synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Kisker C]]
[[Category: Kisker, C.]]
[[Category: Kolappan S]]
[[Category: Kolappan, S.]]
[[Category: Tonge PJ]]
[[Category: Tonge, P J.]]
[[Category: Zhou R]]
[[Category: Zhou, R.]]
[[Category: Zwahlen J]]
[[Category: Zwahlen, J.]]
[[Category: alpha/beta fold]]
 
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