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[[Image:2ev2.gif|left|200px]]


{{Structure
==Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 8.5==
|PDB= 2ev2 |SIZE=350|CAPTION= <scene name='initialview01'>2ev2</scene>, resolution 2.35&Aring;
<StructureSection load='2ev2' size='340' side='right'caption='[[2ev2]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>
<table><tr><td colspan='2'>[[2ev2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EV2 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
|GENE= Rv1264 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ev2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev2 OCA], [https://pdbe.org/2ev2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ev2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ev2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ev2 ProSAT]</span></td></tr>
|RELATEDENTRY=[[1y10|1Y10]], [[1y11|1Y11]], [[2ev1|2EV1]], [[2ev3|2EV3]], [[2ev4|2EV4]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ev2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev2 OCA], [http://www.ebi.ac.uk/pdbsum/2ev2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ev2 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/Y1264_MYCTU Y1264_MYCTU] Catalyzes the formation of the second messenger cAMP.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2ev2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ev2 ConSurf].
<div style="clear:both"></div>


'''Structure of Rv1264N, the regulatory domain of the mycobacterial adenylyl cylcase Rv1264, at pH 8.5'''
==See Also==
 
*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2EV2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV2 OCA].
[[Category: Large Structures]]
[[Category: Adenylate cyclase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Findeisen F]]
[[Category: Findeisen, F.]]
[[Category: Sinning I]]
[[Category: alpha-helical]]
[[Category: Tews I]]
[[Category: regulatory domain of adenylyl cyclase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:54:11 2008''
Retrieved from "https://proteopedia.org/2ev2"