5ybz: Difference between revisions

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'''Unreleased structure'''


The entry 5ybz is ON HOLD  until Paper Publication
==High resolution structure of complement C1q-like protein 3 C1q domain==
 
<StructureSection load='5ybz' size='340' side='right'caption='[[5ybz]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
Authors: Liu, H., Li, Z., Xu, F.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ybz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YBZ FirstGlance]. <br>
Description: High resolution structure of complement C1q-like protein 3 C1q domain
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.711&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Xu, F]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ybz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ybz OCA], [https://pdbe.org/5ybz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ybz RCSB], [https://www.ebi.ac.uk/pdbsum/5ybz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ybz ProSAT]</span></td></tr>
[[Category: Li, Z]]
</table>
[[Category: Liu, H]]
== Function ==
[https://www.uniprot.org/uniprot/C1QL3_MOUSE C1QL3_MOUSE] May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.<ref>PMID:21262840</ref> <ref>PMID:21378161</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Li Z]]
[[Category: Liu H]]
[[Category: Xu F]]
Retrieved from "https://proteopedia.org/5ybz"