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[[Image:2f0e.jpg|left|200px]]


{{Structure
==Crystal structure of Staphylococcal nuclease mutant V23L==
|PDB= 2f0e |SIZE=350|CAPTION= <scene name='initialview01'>2f0e</scene>, resolution 1.95&Aring;
<StructureSection load='2f0e' size='340' side='right'caption='[[2f0e]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2f0e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0E FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
|GENE= nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0e OCA], [https://pdbe.org/2f0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0e RCSB], [https://www.ebi.ac.uk/pdbsum/2f0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0e ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=[[1ey0|1EY0]], [[2exz|2EXZ]], [[2ey1|2EY1]], [[2ey2|2EY2]], [[2ey5|2EY5]], [[2ey6|2EY6]], [[2eyf|2EYF]], [[2eyh|2EYH]], [[2eyj|2EYJ]], [[2eyl|2EYL]], [[2eym|2EYM]], [[2eyo|2EYO]], [[2eyp|2EYP]], [[2f0d|2F0D]], [[2f0f|2F0F]], [[2f0g|2F0G]], [[2f0h|2F0H]], [[2f0i|2F0I]], [[2f0j|2F0J]], [[2f0k|2F0K]], [[2f0l|2F0L]], [[2f0m|2F0M]], [[2f0n|2F0N]], [[2f0o|2F0O]], [[2f0p|2F0P]], [[2f0q|2F0Q]], [[2f0s|2F0S]], [[2f0t|2F0T]], [[2f0u|2F0U]], [[2f0v|2F0V]], [[2f0w|2F0W]]
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0e OCA], [http://www.ebi.ac.uk/pdbsum/2f0e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2f0e RCSB]</span>
[https://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0e ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Staphylococcal nuclease mutant V23L'''
==See Also==
 
*[[Staphylococcal nuclease 3D structures|Staphylococcal nuclease 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2F0E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0E OCA].
[[Category: Large Structures]]
[[Category: Micrococcal nuclease]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Lu, J Z.]]
[[Category: Lu JZ]]
[[Category: Sakon, J.]]
[[Category: Sakon J]]
[[Category: Stites, W E.]]
[[Category: Stites WE]]
[[Category: calcium]]
[[Category: dna hydrolase]]
[[Category: endonuclease]]
[[Category: rna hydrolase]]
[[Category: signal]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:56:14 2008''

Latest revision as of 09:20, 14 February 2024

Crystal structure of Staphylococcal nuclease mutant V23L

2f0e, resolution 1.95Å

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