2fbl: Difference between revisions

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[[Image:2fbl.gif|left|200px]]


{{Structure
==The crystal structure of the hypothetical protein NE1496==
|PDB= 2fbl |SIZE=350|CAPTION= <scene name='initialview01'>2fbl</scene>, resolution 1.90&Aring;
<StructureSection load='2fbl' size='340' side='right'caption='[[2fbl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
<table><tr><td colspan='2'>[[2fbl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBL FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2954 COG2954]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbl OCA], [https://pdbe.org/2fbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fbl RCSB], [https://www.ebi.ac.uk/pdbsum/2fbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbl ProSAT], [https://www.topsan.org/Proteins/MCSG/2fbl TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbl OCA], [http://www.ebi.ac.uk/pdbsum/2fbl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fbl RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/3PASE_NITEU 3PASE_NITEU] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi). The enzyme has a strong preference for linear PPPi compared with cyclic PPPi (cyclic trimetaphosphate) and to the linear P4. The longer chains polyphosphate are not hydrolyzed. It has only a slight thiamine triphosphatase (ThTPase) activity. Nucleoside triphosphatase activity is negligible in the presence of magnesium, but a small activity is observed in the presence of manganese, in particular with GTP.<ref>PMID:21840996</ref>
 
== Evolutionary Conservation ==
'''The crystal structure of the hypothetical protein NE1496'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbl_consurf.spt"</scriptWhenChecked>
2FBL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBL OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fbl ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Nitrosomonas europaea]]
[[Category: Nitrosomonas europaea]]
[[Category: Single protein]]
[[Category: Binkowski TA]]
[[Category: Binkowski, T A.]]
[[Category: Edwards AM]]
[[Category: Edwards, A M.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Lunin VV]]
[[Category: Lunin, V V.]]
[[Category: Onopriyenko O]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Savchenko A]]
[[Category: Onopriyenko, O.]]
[[Category: Skarina T]]
[[Category: Savchenko, A.]]
[[Category: Skarina, T.]]
[[Category: apc5855]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: ne1496]]
[[Category: protein structure initiative]]
[[Category: psi]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:00:34 2008''

Latest revision as of 09:22, 14 February 2024

The crystal structure of the hypothetical protein NE1496

2fbl, resolution 1.90Å

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