2fj2: Difference between revisions

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[[Image:2fj2.jpg|left|200px]]


{{Structure
==Crystal Structure of Viral Macrophage Inflammatory Protein-II==
|PDB= 2fj2 |SIZE=350|CAPTION= <scene name='initialview01'>2fj2</scene>, resolution 2.30&Aring;
<StructureSection load='2fj2' size='340' side='right'caption='[[2fj2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2fj2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ2 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [https://pdbe.org/2fj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj2 ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [http://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB]</span>
[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal Structure of Viral Macrophage Inflammatory Protein-II'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fj/2fj2_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
2FJ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==Reference==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fj2 ConSurf].
Crystal structure of chemically synthesized vMIP-II., Li Y, Liu D, Cao R, Kumar S, Dong C, An J, Wilson SR, Gao YG, Huang Z, Proteins. 2007 Apr 1;67(1):243-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17243149 17243149]
<div style="clear:both"></div>
[[Category: Single protein]]
__TOC__
[[Category: Cao, R.]]
</StructureSection>
[[Category: Dong, C Z.]]
[[Category: Human herpesvirus 8 strain GK18]]
[[Category: Gao, Y G.]]
[[Category: Large Structures]]
[[Category: Huang, Z.]]
[[Category: Cao R]]
[[Category: Kumar, S.]]
[[Category: Dong CZ]]
[[Category: Li, Y.]]
[[Category: Gao YG]]
[[Category: Liu, D.]]
[[Category: Huang Z]]
[[Category: wilson, S R.]]
[[Category: Kumar S]]
[[Category: anti-hiv]]
[[Category: Li Y]]
[[Category: chemokine]]
[[Category: Liu D]]
[[Category: herpesvirus]]
[[Category: Wilson SR]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:03:29 2008''
Retrieved from "https://proteopedia.org/2fj2"