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==Y92H mutant of thermus thermophilus HB8 thymidylate kinase==
==Y92H mutant of thermus thermophilus HB8 thymidylate kinase==
<StructureSection load='5x8v' size='340' side='right' caption='[[5x8v]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
<StructureSection load='5x8v' size='340' side='right'caption='[[5x8v]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5x8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X8V FirstGlance]. <br>
<table><tr><td colspan='2'>[[5x8v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X8V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x86|5x86]], [[5x8a|5x8a]], [[5x8b|5x8b]], [[5x8c|5x8c]], [[5x8d|5x8d]], [[5x8j|5x8j]], [[5x8k|5x8k]], [[5x98|5x98]], [[5x99|5x99]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8v OCA], [https://pdbe.org/5x8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x8v RCSB], [https://www.ebi.ac.uk/pdbsum/5x8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x8v OCA], [http://pdbe.org/5x8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x8v RCSB], [http://www.ebi.ac.uk/pdbsum/5x8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x8v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.  
[https://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
 
==See Also==
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DTMP kinase]]
[[Category: Large Structures]]
[[Category: Chaudhary, S K]]
[[Category: Thermus thermophilus HB8]]
[[Category: Jeyakanthan, J]]
[[Category: Chaudhary SK]]
[[Category: Sekar, K]]
[[Category: Jeyakanthan J]]
[[Category: Nucleotide monophosphate kinase]]
[[Category: Sekar K]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5x8v"