6cqe: Difference between revisions

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New page: '''Unreleased structure''' The entry 6cqe is ON HOLD Authors: Wu, P., Lehoux, I., Mortara, K., Franke, Y., Wang, W. Description: M41-SM apo structure [[Category: Unreleased Structures]...
 
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'''Unreleased structure'''


The entry 6cqe is ON HOLD
==Crystal structure of HPK1 kinase domain S171A mutant==
 
<StructureSection load='6cqe' size='340' side='right'caption='[[6cqe]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
Authors: Wu, P., Lehoux, I., Mortara, K., Franke, Y., Wang, W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6cqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CQE FirstGlance]. <br>
Description: M41-SM apo structure
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.886&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cqe OCA], [https://pdbe.org/6cqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cqe RCSB], [https://www.ebi.ac.uk/pdbsum/6cqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cqe ProSAT]</span></td></tr>
[[Category: Wang, W]]
</table>
[[Category: Wu, P]]
== Function ==
[[Category: Franke, Y]]
[https://www.uniprot.org/uniprot/M4K1_HUMAN M4K1_HUMAN] Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate.<ref>PMID:24362026</ref> <ref>PMID:8824585</ref>
[[Category: Mortara, K]]
== References ==
[[Category: Lehoux, I]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Franke Y]]
[[Category: Lehoux I]]
[[Category: Mortara K]]
[[Category: Wang W]]
[[Category: Wu P]]
Retrieved from "https://proteopedia.org/6cqe"