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| | | #REDIRECT [[6izo]] This PDB entry is obsolete and replaced by 6izo |
| ==Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus==
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| <StructureSection load='5wyp' size='340' side='right' caption='[[5wyp]], [[Resolution|resolution]] 1.80Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[5wyp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WYP FirstGlance]. <br>
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| </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x10|5x10]]</td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyp OCA], [http://pdbe.org/5wyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wyp RCSB], [http://www.ebi.ac.uk/pdbsum/5wyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyp ProSAT]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/DPO3B_CAUCR DPO3B_CAUCR]] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[UniProtKB:P0A988]
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| __TOC__
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| </StructureSection>
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| [[Category: Jiang, X]]
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| [[Category: Li, X]]
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| [[Category: Teng, M]]
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| [[Category: Zhang, L]]
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| [[Category: Dna binding]]
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| [[Category: Homodimer]]
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| [[Category: Protein binding]]
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| [[Category: Transferase]]
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