2g1w: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2g1w.gif|left|200px]]


{{Structure
==NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1==
|PDB= 2g1w |SIZE=350|CAPTION= <scene name='initialview01'>2g1w</scene>
<StructureSection load='2g1w' size='340' side='right'caption='[[2g1w]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
<table><tr><td colspan='2'>[[2g1w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G1W FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [https://pdbe.org/2g1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB], [https://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g1w ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
<div style="background-color:#fffaf0;">
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [http://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB]</span>
== Publication Abstract from PubMed ==
}}
 
'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1'''
 
 
==Overview==
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.


==About this Structure==
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation.,Nonin-Lecomte S, Felden B, Dardel F Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798<ref>PMID:16595798</ref>
2G1W is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA].
 
==Reference==
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16595798 16595798]
[[Category: Protein complex]]
[[Category: Dardel, F.]]
[[Category: Nonin-Lecomte, S.]]
[[Category: nmr]]
[[Category: pk1]]
[[Category: pseudoknot]]
[[Category: tmrna]]
[[Category: trans-translation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:10:41 2008''
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2g1w" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Dardel F]]
[[Category: Nonin-Lecomte S]]
Retrieved from "https://proteopedia.org/2g1w"