5zj8: Difference between revisions
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New page: '''Unreleased structure''' The entry 5zj8 is ON HOLD Authors: Zhang, H., Hao, Q. Description: Crystal structure of NDM-1 in complex with D-captopril derivative CY32 [[Category: Unrelea... |
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==Crystal structure of NDM-1 in complex with D-captopril derivative CY32== | |||
<StructureSection load='5zj8' size='340' side='right'caption='[[5zj8]], [[Resolution|resolution]] 0.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5zj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZJ8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.96Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9DC:(2S)-2,3-disulfanylpropan-1-ol'>9DC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zj8 OCA], [https://pdbe.org/5zj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zj8 RCSB], [https://www.ebi.ac.uk/pdbsum/5zj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zj8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | |||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Hao | [[Category: Klebsiella pneumoniae]] | ||
[[Category: Zhang | [[Category: Large Structures]] | ||
[[Category: Hao Q]] | |||
[[Category: Zhang H]] | |||
