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==Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group P32==
==Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group P32==
<StructureSection load='5tgh' size='340' side='right' caption='[[5tgh]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5tgh' size='340' side='right'caption='[[5tgh]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5tgh]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"chlamydozoon_trachomatis"_(busacca_1935)_moshkovski_1945 "chlamydozoon trachomatis" (busacca 1935) moshkovski 1945] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TGH FirstGlance]. <br>
<table><tr><td colspan='2'>[[5tgh]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydia_trachomatis Chlamydia trachomatis] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TGH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tgj|5tgj]], [[5tgi|5tgi]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SNX5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), incE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=813 "Chlamydozoon trachomatis" (Busacca 1935) Moshkovski 1945])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tgh OCA], [https://pdbe.org/5tgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tgh RCSB], [https://www.ebi.ac.uk/pdbsum/5tgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tgh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tgh OCA], [http://pdbe.org/5tgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tgh RCSB], [http://www.ebi.ac.uk/pdbsum/5tgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tgh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SNX5_HUMAN SNX5_HUMAN]] May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.<ref>PMID:18854019</ref> <ref>PMID:21048941</ref>
[https://www.uniprot.org/uniprot/SNX5_HUMAN SNX5_HUMAN] May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.<ref>PMID:18854019</ref> <ref>PMID:21048941</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Sorting nexin|Sorting nexin]]
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Chlamydia trachomatis]]
[[Category: Collins, B]]
[[Category: Homo sapiens]]
[[Category: Paul, B]]
[[Category: Large Structures]]
[[Category: Host-pathogen endosome]]
[[Category: Collins B]]
[[Category: Protein transport]]
[[Category: Paul B]]
Retrieved from "https://proteopedia.org/5tgh"