6g3m: Difference between revisions
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New page: '''Unreleased structure''' The entry 6g3m is ON HOLD Authors: Dym, O., Aggarwal, N., Albeck, S., Unger, T., Hamer Rogotner, S., Silman, I., Leader, H., Ashani, Y., Goldsmith, M., Greise... |
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==Phosphotriesterase PTE_C23M_4== | |||
<StructureSection load='6g3m' size='340' side='right'caption='[[6g3m]], [[Resolution|resolution]] 1.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6g3m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G3M FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=E8N:1-ethyl-1-methyl-cyclohexane'>E8N</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VX:O-ETHYLMETHYLPHOSPHONIC+ACID+ESTER+GROUP'>VX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6g23|6g23]], [[6g3l|6g3l]], [[6g1j|6g1j]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g3m OCA], [http://pdbe.org/6g3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g3m RCSB], [http://www.ebi.ac.uk/pdbsum/6g3m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g3m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aryldialkylphosphatase]] | |||
[[Category: Large Structures]] | |||
[[Category: Aggarwal, N]] | |||
[[Category: Albeck, S]] | |||
[[Category: Ashani, Y]] | |||
[[Category: Dym, O]] | |||
[[Category: Goldsmith, M]] | |||
[[Category: Greisen, P]] | |||
[[Category: Leader, H]] | [[Category: Leader, H]] | ||
[[Category: | [[Category: Rogotner, S Hamer]] | ||
[[Category: Silman, I]] | [[Category: Silman, I]] | ||
[[Category: Sussman, L J]] | |||
[[Category: Tawfik, D]] | [[Category: Tawfik, D]] | ||
[[Category: | [[Category: Unger, T]] | ||
[[Category: | [[Category: Hydrolase]] | ||
[[Category: | [[Category: Metalloenzyme]] | ||
[[Category: Tim barrel]] | |||
