1fsl: Difference between revisions

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==FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE==
==FERRIC SOYBEAN LEGHEMOGLOBIN COMPLEXED WITH NICOTINATE==
<StructureSection load='1fsl' size='340' side='right' caption='[[1fsl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1fsl' size='340' side='right'caption='[[1fsl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fsl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FSL FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fsl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FSL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fsl OCA], [http://pdbe.org/1fsl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fsl RCSB], [http://www.ebi.ac.uk/pdbsum/1fsl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fsl ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NIO:NICOTINIC+ACID'>NIO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fsl OCA], [https://pdbe.org/1fsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fsl RCSB], [https://www.ebi.ac.uk/pdbsum/1fsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fsl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LGBA_SOYBN LGBA_SOYBN]] Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.  
[https://www.uniprot.org/uniprot/LGB3_SOYBN LGB3_SOYBN] Leghemoglobin that reversibly binds oxygen O(2) through a pentacoordinated heme iron (PubMed:29100196). In root nodules, facilitates the diffusion of oxygen to the bacteroids while preventing the bacterial nitrogenase from being inactivated by buffering dioxygen, nitric oxide and carbon monoxide, and promoting the formation of reactive oxygen species (ROS, e.g. H(2)O(2)) (PubMed:17540516, PubMed:22308405, PubMed:29701804, PubMed:32297921). This role is essential for symbiotic nitrogen fixation (SNF) (PubMed:17540516, PubMed:32297921).<ref>PMID:22308405</ref> <ref>PMID:29100196</ref> <ref>PMID:29701804</ref> <ref>PMID:32297921</ref> <ref>PMID:17540516</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/1fsl_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/1fsl_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Glycine max]]
[[Category: Glycine max]]
[[Category: Ellis, P J]]
[[Category: Large Structures]]
[[Category: Freeman, H C]]
[[Category: Ellis PJ]]
[[Category: Guss, J M]]
[[Category: Freeman HC]]
[[Category: Heme]]
[[Category: Guss JM]]
[[Category: Multigene family]]
[[Category: Nitrogen fixation]]
[[Category: Oxygen transport]]
[[Category: Respiratory protein]]
Retrieved from "https://proteopedia.org/1fsl"