2dhb: Difference between revisions
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==THREE DIMENSIONAL FOURIER SYNTHESIS OF HORSE DEOXYHAEMOGLOBIN AT 2.8 ANGSTROMS RESOLUTION== | ==THREE DIMENSIONAL FOURIER SYNTHESIS OF HORSE DEOXYHAEMOGLOBIN AT 2.8 ANGSTROMS RESOLUTION== | ||
<StructureSection load='2dhb' size='340' side='right' caption='[[2dhb]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='2dhb' size='340' side='right'caption='[[2dhb]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dhb]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2dhb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. The May 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Hemoglobin'' by Shuchismita Dutta and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_5 10.2210/rcsb_pdb/mom_2003_5]. The October 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DHB FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dhb OCA], [https://pdbe.org/2dhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dhb RCSB], [https://www.ebi.ac.uk/pdbsum/2dhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dhb ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE] Involved in oxygen transport from the lung to the various peripheral tissues. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/2dhb_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dh/2dhb_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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[[Category: Equus caballus]] | [[Category: Equus caballus]] | ||
[[Category: Hemoglobin]] | [[Category: Hemoglobin]] | ||
[[Category: Large Structures]] | |||
[[Category: PDB Pioneers]] | [[Category: PDB Pioneers]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Perutz | [[Category: Perutz MF]] | ||
Latest revision as of 07:54, 13 August 2026
THREE DIMENSIONAL FOURIER SYNTHESIS OF HORSE DEOXYHAEMOGLOBIN AT 2.8 ANGSTROMS RESOLUTION
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