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==The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution==
==The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution==
<StructureSection load='1vdq' size='340' side='right' caption='[[1vdq]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='1vdq' size='340' side='right'caption='[[1vdq]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vdq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VDQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VDQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vdq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VDQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VDQ FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vdp|1vdp]], [[1vds|1vds]], [[1vdt|1vdt]], [[1ved|1ved]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vdq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdq OCA], [https://pdbe.org/1vdq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vdq RCSB], [https://www.ebi.ac.uk/pdbsum/1vdq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vdq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vdq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdq OCA], [http://pdbe.org/1vdq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vdq RCSB], [http://www.ebi.ac.uk/pdbsum/1vdq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vdq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vdq_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vdq_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Large Structures]]
[[Category: Aibara, S]]
[[Category: Aibara S]]
[[Category: DeLucas, L J]]
[[Category: DeLucas LJ]]
[[Category: Hirose, M]]
[[Category: Hirose M]]
[[Category: Kidera, A]]
[[Category: Kidera A]]
[[Category: Shibata, K]]
[[Category: Shibata K]]
[[Category: Suzuki, A]]
[[Category: Suzuki A]]
[[Category: Yamane, T]]
[[Category: Yamane T]]
[[Category: Hen egg white]]
[[Category: Hydrolase]]
[[Category: Orthrhombic]]

Latest revision as of 07:29, 9 October 2024

The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution

1vdq, resolution 1.50Å

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