1vcw: Difference between revisions

<StructureSection load='1vcw' size='340' side='right'caption='[[1vcw]], [[Resolution|resolution]] 3.05&Aring;' scene=''>

<table><tr><td colspan='2'>[[1vcw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCW FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcw OCA], [https://pdbe.org/1vcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcw RCSB], [https://www.ebi.ac.uk/pdbsum/1vcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcw ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/DEGS_ECOLI DEGS_ECOLI] When heat shock or other environmental stresses disrupt protein folding in the periplasm, DegS senses the accumulation of unassembled outer membrane porins (OMPs) and then initiates RseA (anti sigma-E factor) degradation by cleaving it in its periplasmic domain, making it an attractive substrate for subsequent cleavage by RseP. This cascade that ultimately leads to the sigma-E-driven expression of a variety of factors dealing with folding stress in the periplasm and OMP assembly.<ref>PMID:12183369</ref> <ref>PMID:19695325</ref>  

[[Category: Escherichia coli]]

[[Category: Large Structures]]

[[Category: Clausen T]]

[[Category: Ehrmann M]]

[[Category: Kitzing K]]

[[Category: Kurzbauer R]]

[[Category: Wilken C]]