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| *[[Krebs cycle importance]] | | *[[Krebs cycle importance]] |
| *[[Krebs cycle overview]] | | *[[Krebs cycle overview]] |
| | *[[Krebs cycle reactions]] |
| | *[[Citric Acid Cycle]] |
| *[[Krebs cycle step 1]] | | *[[Krebs cycle step 1]] |
| | *[[Glyoxylate cycle]] |
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| | '''2-methylcitrate synthase''' catabolizes propionate to succinate and pyruvate<ref>PMID:9579066</ref>. |
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| ==Structure== | | ==Structure== |
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| *<scene name='Citrate_Synthase/Cv/1'>Citrate Synthase Closed Form (Monomer)</scene> [[2cts]] | | *<scene name='Citrate_Synthase/Cv/1'>Citrate Synthase Closed Form (Monomer)</scene> [[2cts]] |
| *<scene name='Citrate_Synthase/Cv/2'>'Citrate Synthase Open Form (Monomer)</scene> [[1cts]] | | *<scene name='Citrate_Synthase/Cv/2'>'Citrate Synthase Open Form (Monomer)</scene> [[1cts]] |
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| | ==3D structures of Citrate Synthase== |
| | [[Citrate Synthase 3D structures]] |
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| </StructureSection> | | </StructureSection> |
| __NOTOC__ | | __NOTOC__ |
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| [[Image:2cts plus overall reaction.png|500px|left|thumb| <span style="font-size:1.2em;">Citrate synthase 'closed' form complex with CoA and citrate ([[2cts]]) and the reaction</span>]] | | [[Image:2cts plus overall reaction.png|500px|left|thumb| <span style="font-size:1.2em;">Citrate synthase 'closed' form complex with CoA and citrate ([[2cts]]) and the reaction</span>]] |
| {{Clear}} | | {{Clear}} |
| ==3D structures of Citrate Synthase==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *Citrate synthase
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| **[[3msu]] – CitS – ''Francisella tularensis''<br />
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| **[[3enj]] – CitS – Wild boar<br />
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| **[[2p2w]] – CitS – ''Thermotoga maritima''<br />
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| **[[2c6x]] – CitS residues 2-364 – ''Bacillus subtilis''<br />
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| **[[1owc]], [[1nxe]], [[4jad]] – EcCitS (mutant) – ''Eschericia coli''<br />
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| **[[4g6b]] – EcCitS II<br />
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| **[[2ibp]] – CitS – ''Pyrobaculum aerophilum''<br />
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| **[[1iom]], [[1ixe]] – CitS – ''Thermus thermophilus''<br />
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| **[[1o7x]] – CitS – ''Sulfolobus solfataricus''<br />
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| **[[1a59]] – CitS – ''Antarctic bacterium''<br />
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| **[[1aj8]] – CitS - ''Pyrococcus furiosus''<br />
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| **[[5csc]], [[3cts]]– cCitS – chicken<br />
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| **[[1cts]], [[2cts]] – pCitS - pig<br />
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| **[[4e6y]] – CitS – ''Vibrio vulnificus''<br />
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| **[[4tvm]] – MtCitS – ''Mycobacterium tuberculosis''<br />
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| **[[4xgh]] – CitS – ''Burkholderia thailandensis''<br />
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| **[[4ybo]] - TaCitS – ''Thermoplasma acidophilum''<br />
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| **[[5uzq]], [[5uzr]] - hCitS – human<br />
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| *Citrate synthase binary complex
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| **[[4jae]] - EcCitS (mutant) + S-carboxymethyl-CoA<br />
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| **[[2r9e]] – TaCitS + citryl dethia CoA <br />
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| **[[6cts]] – cCitS + citryl thioether CoA<br />
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| **[[1owb]], [[1nxg]], [[4jaf]] - EcCitS (mutant) + NADH<br />
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| **[[4jag]] - EcCitS (mutant) + oxaloacetate<br />
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| **[[2ifc]] - TaCitS + oxaloacetate<br />
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| **[[5uzp]] - hCitS (mutant) + oxaloacetate <br />
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| *Citrate synthase ternary complex
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| **[[2r26]] - TaCitS + oxaloacetate + S-carboxymethyl-CoA<br />
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| **[[2h12]] - CitS + oxaloacetate + carboxymethyl dethia-CoA – ''Acetobacter aceti''<br />
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| **[[1al6]], [[1csr]], [[1css]], [[1csh]], [[1csi]] - cCitS + oxaloacetate + carboxymethyl dethia-CoA derivative<br />
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| **[[5cts]], [[6cts]] - cCitS + oxaloacetate + carboxymethyl CoA<br />
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| **[[1amz]] - cCitS + malate + nitromethyl dethia-CoA<br />
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| **[[1csc]], [[2csc]], [[3csc]], [[4csc]] - cCitS + malate + carboxymethyl CoA<br />
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| **[[6csc]] - cCitS + citrate + trifluoroacetonyl-CoA<br />
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| **[[4cts]] - pCitS + oxaloacetate + S-acetonyl CoA<br />
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| * ATP-Citrate synthase see [[ATP-Citrate synthase]]
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| * Methylcitrate synthase
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| **[[3hwk]] – MtMCitS <br />
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| **[[3tqg]] – 2-MCitS – ''Coxiella burnetii''<br />
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| **[[3o8j]] – 2-MCitS – ''Salmonella enterica''<br />
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| }}
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| ==See Also== | | ==See Also== |
