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[[Image:2gup.gif|left|200px]]


{{Structure
==Structural Genomics, the crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose==
|PDB= 2gup |SIZE=350|CAPTION= <scene name='initialview01'>2gup</scene>, resolution 2.01&Aring;
<StructureSection load='2gup' size='340' side='right'caption='[[2gup]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
<table><tr><td colspan='2'>[[2gup]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GUP FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1940 NagC], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00480 ROK]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gup OCA], [https://pdbe.org/2gup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gup RCSB], [https://www.ebi.ac.uk/pdbsum/2gup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gup ProSAT], [https://www.topsan.org/Proteins/MCSG/2gup TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gup OCA], [http://www.ebi.ac.uk/pdbsum/2gup PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gup RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/A0A0H2USG4_STRPN A0A0H2USG4_STRPN]
 
== Evolutionary Conservation ==
'''Structural Genomics, the crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2gup_consurf.spt"</scriptWhenChecked>
2GUP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUP OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Streptococcus pneumoniae]]
  </jmolCheckbox>
[[Category: Abdullah, J.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gup ConSurf].
[[Category: Joachimiak, A.]]
<div style="clear:both"></div>
[[Category: Li, H.]]
__TOC__
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</StructureSection>
[[Category: Tan, K.]]
[[Category: Large Structures]]
[[Category: apc80695]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: mcsg]]
[[Category: Abdullah J]]
[[Category: midwest center for structural genomic]]
[[Category: Joachimiak A]]
[[Category: protein structure initiative]]
[[Category: Li H]]
[[Category: psi]]
[[Category: Tan K]]
[[Category: rok family]]
[[Category: streptococcus pneumoniae tigr4]]
[[Category: structural genomic]]
[[Category: sucrose]]
[[Category: sugar kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:21:50 2008''

Latest revision as of 00:59, 21 November 2024

Structural Genomics, the crystal structure of a ROK family protein from Streptococcus pneumoniae TIGR4 in complex with sucrose

2gup, resolution 2.01Å

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