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==LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOBIOSE==
==LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOBIOSE==
<StructureSection load='1bb7' size='340' side='right' caption='[[1bb7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1bb7' size='340' side='right'caption='[[1bb7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1bb7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oncorhynchus_mykiss Oncorhynchus mykiss]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BB7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1bb7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oncorhynchus_mykiss Oncorhynchus mykiss]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BB7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GUM:4-METHYL-UMBELLIFERYL-N-ACETYL-CHITOBIOSE'>GUM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GUM:4-METHYL-UMBELLIFERYL-N-ACETYL-CHITOBIOSE'>GUM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bb7 OCA], [http://pdbe.org/1bb7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bb7 RCSB], [http://www.ebi.ac.uk/pdbsum/1bb7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bb7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bb7 OCA], [https://pdbe.org/1bb7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bb7 RCSB], [https://www.ebi.ac.uk/pdbsum/1bb7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bb7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LYSC2_ONCMY LYSC2_ONCMY]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has antibacterial activity against the Gram positive bacterium P.citreus. Has no antibacterial activity against the Gram negative bacteria E.coli and Y.ruckeri. Does not have hemolytic activity against trout erythrocytes.<ref>PMID:15142536</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bb7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bb7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lysozyme]]
[[Category: Large Structures]]
[[Category: Oncorhynchus mykiss]]
[[Category: Oncorhynchus mykiss]]
[[Category: Hough, E]]
[[Category: Hough E]]
[[Category: Karlsen, S]]
[[Category: Karlsen S]]
[[Category: Vollan, V B]]
[[Category: Vollan VB]]
[[Category: Hydrolase]]
[[Category: N-acetyl-muramidase]]
[[Category: Umbelliferone glycoside]]

Latest revision as of 23:49, 20 November 2024

LYSOZYME COMPLEX WITH 4-METHYL-UMBELLIFERYL CHITOBIOSE

1bb7, resolution 2.00Å

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