5uuy: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of Dioclea lasiocarpa lectin (DLL) complexed with X-MAN== | ==Crystal structure of Dioclea lasiocarpa lectin (DLL) complexed with X-MAN== | ||
<StructureSection load='5uuy' size='340' side='right' caption='[[5uuy]], [[Resolution|resolution]] 1.88Å' scene=''> | <StructureSection load='5uuy' size='340' side='right'caption='[[5uuy]], [[Resolution|resolution]] 1.88Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5uuy]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5uuy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dioclea Dioclea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UUY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uuy OCA], [https://pdbe.org/5uuy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uuy RCSB], [https://www.ebi.ac.uk/pdbsum/5uuy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uuy ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LECA_DIOVI LECA_DIOVI] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.[REFERENCE:1]<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 24: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Dioclea]] | [[Category: Dioclea]] | ||
[[Category: Cavada | [[Category: Large Structures]] | ||
[[Category: Fonseca | [[Category: Cavada BS]] | ||
[[Category: Nascimento | [[Category: Fonseca FMP]] | ||
[[Category: Neco | [[Category: Nascimento KS]] | ||
[[Category: Osterne | [[Category: Neco AHB]] | ||
[[Category: Pinto-Junior | [[Category: Osterne VJS]] | ||
[[Category: Rocha | [[Category: Pinto-Junior VR]] | ||
[[Category: Santiago | [[Category: Rocha CRC]] | ||
[[Category: Santiago MQ]] | |||
Latest revision as of 13:34, 4 October 2023
Crystal structure of Dioclea lasiocarpa lectin (DLL) complexed with X-MAN
| ||||||||||||
