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==Crystal structure of P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli==
==Crystal structure of P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli==
<StructureSection load='1xcf' size='340' side='right' caption='[[1xcf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1xcf' size='340' side='right'caption='[[1xcf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xcf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xcf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XCF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k8x|1k8x]], [[1xc4|1xc4]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xcf OCA], [https://pdbe.org/1xcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xcf RCSB], [https://www.ebi.ac.uk/pdbsum/1xcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xcf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xcf OCA], [http://pdbe.org/1xcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xcf RCSB], [http://www.ebi.ac.uk/pdbsum/1xcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xcf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRPA_ECOLI TRPA_ECOLI]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.  
[https://www.uniprot.org/uniprot/TRPA_ECOLI TRPA_ECOLI] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Tryptophan synthase|Tryptophan synthase]]
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Tryptophan synthase]]
[[Category: Large Structures]]
[[Category: Jang, S B]]
[[Category: Jang SB]]
[[Category: A-subunit]]
[[Category: E coli]]
[[Category: Lyase]]
[[Category: P28l/y173f double mutant]]
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