2h7h: Difference between revisions

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[[Image:2h7h.gif|left|200px]]


{{Structure
==Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA==
|PDB= 2h7h |SIZE=350|CAPTION= <scene name='initialview01'>2h7h</scene>, resolution 2.30&Aring;
<StructureSection load='2h7h' size='340' side='right'caption='[[2h7h]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
<table><tr><td colspan='2'>[[2h7h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_sarcoma_virus Avian sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H7H FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h7h OCA], [https://pdbe.org/2h7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h7h RCSB], [https://www.ebi.ac.uk/pdbsum/2h7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h7h ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h7h OCA], [http://www.ebi.ac.uk/pdbsum/2h7h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h7h RCSB]</span>
[https://www.uniprot.org/uniprot/JUN_AVIS1 JUN_AVIS1] This oncogene is the viral derivative of the AP-1 transcription factor.
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/2h7h_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2H7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Avian_sarcoma_virus Avian sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H7H OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h7h ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Avian sarcoma virus]]
[[Category: Avian sarcoma virus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Borovilos, M.]]
[[Category: Borovilos M]]
[[Category: Cuff, M E.]]
[[Category: Cuff ME]]
[[Category: Kim, Y.]]
[[Category: Kim Y]]
[[Category: Rajan, S S.]]
[[Category: Rajan SS]]
[[Category: leucine zipper]]
[[Category: protein-dna complex]]
[[Category: transcription]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:26:34 2008''
Retrieved from "https://proteopedia.org/2h7h"