2hlz: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2hlz.gif|left|200px]]


{{Structure
==Crystal Structure of human ketohexokinase==
|PDB= 2hlz |SIZE=350|CAPTION= <scene name='initialview01'>2hlz</scene>, resolution 1.850&Aring;
<StructureSection load='2hlz' size='340' side='right'caption='[[2hlz]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>
<table><tr><td colspan='2'>[[2hlz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HLZ FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ketohexokinase Ketohexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.3 2.7.1.3] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
|GENE= KHK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlz OCA], [https://pdbe.org/2hlz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hlz RCSB], [https://www.ebi.ac.uk/pdbsum/2hlz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hlz ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlz OCA], [http://www.ebi.ac.uk/pdbsum/2hlz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hlz RCSB]</span>
== Evolutionary Conservation ==
}}
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/2hlz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hlz ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of human ketohexokinase (CASP Target)'''
==See Also==
 
*[[Ketohexokinase|Ketohexokinase]]
 
__TOC__
==Disease==
</StructureSection>
Known disease associated with this structure: Fructosuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=229800 229800]]
 
==About this Structure==
2HLZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLZ OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ketohexokinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C H.]]
[[Category: Bochkarev A]]
[[Category: Bochkarev, A.]]
[[Category: Edwards AM]]
[[Category: Edwards, A M.]]
[[Category: Landry R]]
[[Category: Landry, R.]]
[[Category: Nedyalkova L]]
[[Category: Nedyalkova, L.]]
[[Category: Park H]]
[[Category: Park, H.]]
[[Category: Rabeh WM]]
[[Category: Rabeh, W M.]]
[[Category: Sundstrom M]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Tempel W]]
[[Category: Sundstrom, M.]]
[[Category: Weigelt J]]
[[Category: Tempel, W.]]
[[Category: Weigelt, J.]]
[[Category: creatine kinase]]
[[Category: fructokinase]]
[[Category: isoform some]]
[[Category: non-protein kinase]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:32:13 2008''
Retrieved from "https://proteopedia.org/2hlz"