5o9y: Difference between revisions

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==Crystal structure of ScGas2 in complex with compound 11==
==Crystal structure of ScGas2 in complex with compound 11==
<StructureSection load='5o9y' size='340' side='right' caption='[[5o9y]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='5o9y' size='340' side='right'caption='[[5o9y]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5o9y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O9Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[5o9y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O9Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9PN:(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[4-(3-pyridin-1-ium-1-ylpropyl)-1,2,3-triazol-1-yl]oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol'>9PN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9y OCA], [http://pdbe.org/5o9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o9y RCSB], [http://www.ebi.ac.uk/pdbsum/5o9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9y ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9PN:(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[4-(3-pyridin-1-ium-1-ylpropyl)-1,2,3-triazol-1-yl]oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol'>9PN</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9y OCA], [https://pdbe.org/5o9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o9y RCSB], [https://www.ebi.ac.uk/pdbsum/5o9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST]] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>
[https://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aalten, D Van]]
[[Category: Large Structures]]
[[Category: Castro-Lopez, J]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Delso, I]]
[[Category: Castro-Lopez J]]
[[Category: Fang, W]]
[[Category: Delso I]]
[[Category: Gomollon-Bel, F]]
[[Category: Fang W]]
[[Category: Hurtado-Guerrero, R]]
[[Category: Gomollon-Bel F]]
[[Category: Merino, P]]
[[Category: Hurtado-Guerrero R]]
[[Category: Navratilova, I]]
[[Category: Merino P]]
[[Category: Tejero, T]]
[[Category: Navratilova I]]
[[Category: Valero-Gonzalez, J]]
[[Category: Tejero T]]
[[Category: Afgel4]]
[[Category: Valero-Gonzalez J]]
[[Category: Aspergillus fumigatus]]
[[Category: Van Aalten D]]
[[Category: Cell wall remodeling]]
[[Category: Fungal cell wall]]
[[Category: Glucanosyltransferase]]
[[Category: Scgas2]]
[[Category: Transferase]]
[[Category: Transglycosylase]]

Latest revision as of 09:38, 6 December 2023

Crystal structure of ScGas2 in complex with compound 11

5o9y, resolution 1.57Å

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