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[[Image:2hpz.gif|left|200px]]


{{Structure
==Crystal structure of proteinase K complex with a synthetic peptide KLKLLVVIRLK at 1.69 A resolution==
|PDB= 2hpz |SIZE=350|CAPTION= <scene name='initialview01'>2hpz</scene>, resolution 1.69&Aring;
<StructureSection load='2hpz' size='340' side='right'caption='[[2hpz]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>
<table><tr><td colspan='2'>[[2hpz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HPZ FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hpz OCA], [https://pdbe.org/2hpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hpz RCSB], [https://www.ebi.ac.uk/pdbsum/2hpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hpz ProSAT]</span></td></tr>
|RELATEDENTRY=[[1p7v|1P7V]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hpz OCA], [http://www.ebi.ac.uk/pdbsum/2hpz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hpz RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hp/2hpz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hpz ConSurf].
<div style="clear:both"></div>


'''Crystal structure of proteinase K complex with a synthetic peptide KLKLLVVIRLK at 1.69 A resolution'''
==See Also==
 
*[[Proteinase 3D structures|Proteinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2HPZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HPZ OCA].
[[Category: Large Structures]]
[[Category: Engyodontium album]]
[[Category: Parengyodontium album]]
[[Category: Peptidase K]]
[[Category: Bhushan A]]
[[Category: Single protein]]
[[Category: Dey S]]
[[Category: Bhushan, A.]]
[[Category: Kaur P]]
[[Category: Dey, S.]]
[[Category: Prem kumar R]]
[[Category: Kaur, P.]]
[[Category: Sharma S]]
[[Category: Sharma, S.]]
[[Category: Singh AK]]
[[Category: Singh, A K.]]
[[Category: Singh N]]
[[Category: Singh, N.]]
[[Category: Singh TP]]
[[Category: Singh, T P.]]
[[Category: Somvanshi RK]]
[[Category: Somvanshi, R K.]]
[[Category: kumar, R Prem.]]
[[Category: complex]]
[[Category: peptide complex]]
[[Category: proteinase k]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:33:43 2008''
Retrieved from "https://proteopedia.org/2hpz"