Beta Amyloid forms Plaques: Difference between revisions
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Katie Agosta (talk | contribs) New page: == Background == Amyloids are accumulated proteins that are folded up into a shape that allows for continual copies to be made of each protein. These proteins then create fibrils that is g... |
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<Structure load='2MXU' size='350' frame='true' align='right' caption='42-Residue Beta Amyloid Fibril (PDB code [[2mxu]])' /> | |||
Amyloid | |||
== Background == | == Background == | ||
Amyloids are accumulated proteins that are folded up into a shape that allows for continual copies to be made of each protein. These proteins then create fibrils that is generated in the bone marrow and deposited throughout all organs and tissues. Numerous diseases can be credited to the over abundance of amyloid fibrils. Amyloids can be formed by many different proteins and polypeptides. Amyloids are formed by polymerization of monomeric peptides into fibers. It takes thousands and thousands to create a single fiber of amyloid. The formation relies on the sequance heavily, meaning any mutations can cause the assembly process to shut down. | Amyloids are accumulated proteins that are folded up into a shape that allows for continual copies to be made of each protein. These proteins then create fibrils that is generated in the bone marrow and deposited throughout all organs and tissues. Numerous diseases can be credited to the over abundance of amyloid fibrils. Amyloids can be formed by many different proteins and polypeptides. Amyloids are formed by polymerization of monomeric peptides into fibers. It takes thousands and thousands to create a single fiber of amyloid. The formation relies on the sequance heavily, meaning any mutations can cause the assembly process to shut down. | ||
