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[[Image:2htt.gif|left|200px]]


{{Structure
==Ruthenium Hexammine ion interactions with Z-DNA==
|PDB= 2htt |SIZE=350|CAPTION= <scene name='initialview01'>2htt</scene>, resolution 2.60&Aring;
<StructureSection load='2htt' size='340' side='right'caption='[[2htt]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene>
<table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HTT FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htt OCA], [https://pdbe.org/2htt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2htt RCSB], [https://www.ebi.ac.uk/pdbsum/2htt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2htt ProSAT]</span></td></tr>
|RELATEDENTRY=[[2hto|2HTO]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htt OCA], [http://www.ebi.ac.uk/pdbsum/2htt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2htt RCSB]</span>
<div style="background-color:#fffaf0;">
}}
== Publication Abstract from PubMed ==
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.


'''Ruthenium Hexammine ion interactions with Z-DNA'''
Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2htt" style="background-color:#fffaf0;"></div>


==About this Structure==
==See Also==
2HTT is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA].
*[[Z-DNA|Z-DNA]]
[[Category: Protein complex]]
== References ==
[[Category: Bharanidharan, D.]]
<references/>
[[Category: Gautham, N.]]
__TOC__
[[Category: Thiyagarajan, S.]]
</StructureSection>
[[Category: double helix]]
[[Category: Large Structures]]
[[Category: z-dna]]
[[Category: Bharanidharan D]]
 
[[Category: Gautham N]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:35:18 2008''
[[Category: Thiyagarajan S]]

Latest revision as of 08:13, 13 August 2026

Ruthenium Hexammine ion interactions with Z-DNA

2htt, resolution 2.60Å

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