5zua: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "5zua" [edit=sysop:move=sysop] |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of MERS-CoV macro domain in complex with ATP== | |||
<StructureSection load='5zua' size='340' side='right'caption='[[5zua]], [[Resolution|resolution]] 2.47Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5zua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZUA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.471Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zua OCA], [https://pdbe.org/5zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zua RCSB], [https://www.ebi.ac.uk/pdbsum/5zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zua ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/T2B9G2_MERS T2B9G2_MERS] Catalytic subunit of viral RNA capping enzyme which catalyzes the RNA guanylyltransferase reaction for genomic and sub-genomic RNAs. The kinase-like NiRAN domain of NSP12 transfers RNA to the amino terminus of NSP9, forming a covalent RNA-protein intermediate. Subsequently, the NiRAN domain transfers RNA to GDP, forming the core cap structure GpppA-RNA. The NSP14 and NSP16 methyltransferases then add methyl groups to form functional cap structures.[ARBA:ARBA00034461] | |||
==See Also== | |||
*[[Virus protease 3D structures|Virus protease 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Chien | [[Category: Large Structures]] | ||
[[Category: Cho | [[Category: Middle East respiratory syndrome-related coronavirus]] | ||
[[Category: Hsu | [[Category: Chien C-Y]] | ||
[[Category: Lin | [[Category: Cho C-C]] | ||
[[Category: Hsu C-H]] | |||
[[Category: Lin M-H]] | |||
Latest revision as of 09:07, 22 November 2023
Crystal structure of MERS-CoV macro domain in complex with ATP
| ||||||||||||
