2ife: Difference between revisions

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[[Image:2ife.gif|left|200px]]


{{Structure
==TRANSLATION INITIATION FACTOR IF3 FROM ESCHERICHIA COLI RIBOSOME BINDING DOMAIN (RESIDUES 84-180)==
|PDB= 2ife |SIZE=350|CAPTION= <scene name='initialview01'>2ife</scene>
<StructureSection load='2ife' size='340' side='right'caption='[[2ife]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2ife]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ife 1ife]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IFE FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= INFC CODONS 84-180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ife OCA], [https://pdbe.org/2ife PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ife RCSB], [https://www.ebi.ac.uk/pdbsum/2ife PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ife ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ife OCA], [http://www.ebi.ac.uk/pdbsum/2ife PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ife RCSB]</span>
[https://www.uniprot.org/uniprot/IF3_ECOLI IF3_ECOLI] IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.[HAMAP-Rule:MF_00080]
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''TRANSLATION INITIATION FACTOR IF3 FROM ESCHERICHIA COLI RIBOSOME BINDING DOMAIN (RESIDUES 84-180)'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/if/2ife_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
2IFE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry 1IFE. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFE OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ife ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Cock, E De.]]
[[Category: Dardel F]]
[[Category: Dardel, F.]]
[[Category: De Cock E]]
[[Category: Garcia, C.]]
[[Category: Garcia C]]
[[Category: initiation factor]]
 
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