2ihc: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2ihc.gif|left|200px]]


{{Structure
==Crystal structure of the bric-a-brac (BTB) domain of human BACH1==
|PDB= 2ihc |SIZE=350|CAPTION= <scene name='initialview01'>2ihc</scene>, resolution 2.44&Aring;
<StructureSection load='2ihc' size='340' side='right'caption='[[2ihc]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHC FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.44&#8491;</td></tr>
|GENE= BACH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [https://pdbe.org/2ihc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB], [https://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihc ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [http://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB]</span>
[https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of the bric-a-brac (BTB) domain of human BACH1'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/2ihc_consurf.spt"</scriptWhenChecked>
==Disease==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
Known disease associated with this structure: Breast cancer, early-onset OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605882 605882]], Fanconi anemia, complementation group J OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605882 605882]]
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ihc ConSurf].
2IHC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA].  
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Amos, A L.]]
[[Category: Amos AL]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith C]]
[[Category: Bullock, A.]]
[[Category: Bullock A]]
[[Category: Bunkoczi, G.]]
[[Category: Bunkoczi G]]
[[Category: Delft, F von.]]
[[Category: Edwards A]]
[[Category: Edwards, A.]]
[[Category: Gorrec F]]
[[Category: Gorrec, F.]]
[[Category: Knapp S]]
[[Category: Knapp, S.]]
[[Category: Papagrigoriou E]]
[[Category: Papagrigoriou, E.]]
[[Category: Sundstrom M]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Turnbull AP]]
[[Category: Sundstrom, M.]]
[[Category: Umeano C]]
[[Category: Turnbull, A P.]]
[[Category: Weigelt J]]
[[Category: Umeano, C.]]
[[Category: Von Delft F]]
[[Category: Weigelt, J.]]
[[Category: bach1]]
[[Category: bric-a-brac domain,transcription factor]]
[[Category: cap'n'collar type of basic region leucine zipper factor family]]
[[Category: protein-protein interaction]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:44:21 2008''

Latest revision as of 10:11, 30 August 2023

Crystal structure of the bric-a-brac (BTB) domain of human BACH1

2ihc, resolution 2.44Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=2ihc&oldid=3851765"