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==Complexes of Dodecin with Flavin and Flavin-like Ligands==
==Complexes of Dodecin with Flavin and Flavin-like Ligands==
<StructureSection load='2cc9' size='340' side='right' caption='[[2cc9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='2cc9' size='340' side='right'caption='[[2cc9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hals3 Hals3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CC9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_R1 Halobacterium salinarum R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CC9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mog|1mog]], [[2cc6|2cc6]], [[2cc7|2cc7]], [[2cc8|2cc8]], [[2ccb|2ccb]], [[2ccc|2ccc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cc9 OCA], [http://pdbe.org/2cc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cc9 RCSB], [http://www.ebi.ac.uk/pdbsum/2cc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cc9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cc9 OCA], [https://pdbe.org/2cc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cc9 RCSB], [https://www.ebi.ac.uk/pdbsum/2cc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cc9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DODEC_HALS3 DODEC_HALS3] May function as storage protein that sequesters riboflavin and related compounds, thereby protecting the cell against undesirable reactions mediated by the free flavins. Binds and sequesters riboflavin, lumiflavin and lumichrome. Can also bind FAD and FMN (in vitro), but has low affinity for FAD and even lower affinity for FMN. Protects bound flavins against light damage; Trp-36 rapidly quenches the flavin excited state. Promotes the conversion of bound riboflavin to lumichrome.<ref>PMID:12679016</ref> <ref>PMID:16460756</ref> <ref>PMID:17027852</ref> <ref>PMID:19224924</ref> <ref>PMID:20408700</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hals3]]
[[Category: Halobacterium salinarum R1]]
[[Category: Grininger, M]]
[[Category: Large Structures]]
[[Category: Oesterhelt, D]]
[[Category: Grininger M]]
[[Category: Zeth, K]]
[[Category: Oesterhelt D]]
[[Category: Flavin]]
[[Category: Zeth K]]
[[Category: Flavin-like ligand]]
[[Category: Flavoprotein]]
Retrieved from "https://proteopedia.org/2cc9"