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==Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like==
==Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like==
<StructureSection load='2cuj' size='340' side='right' caption='[[2cuj]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2cuj' size='340' side='right'caption='[[2cuj]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cuj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CUJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cuj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUJ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tada2l ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cuj OCA], [http://pdbe.org/2cuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cuj RCSB], [http://www.ebi.ac.uk/pdbsum/2cuj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cuj ProSAT], [http://www.topsan.org/Proteins/RSGI/2cuj TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cuj OCA], [https://pdbe.org/2cuj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cuj RCSB], [https://www.ebi.ac.uk/pdbsum/2cuj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cuj ProSAT], [https://www.topsan.org/Proteins/RSGI/2cuj TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TAD2A_MOUSE TAD2A_MOUSE]] Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling (By similarity).  
[https://www.uniprot.org/uniprot/TAD2A_MOUSE TAD2A_MOUSE] Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Mus musculus]]
[[Category: Kigawa, T]]
[[Category: Inoue M]]
[[Category: Koshiba, S]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Koshiba S]]
[[Category: Sato, M]]
[[Category: Sato M]]
[[Category: Tanaka, A]]
[[Category: Tanaka A]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Umehara, T]]
[[Category: Umehara T]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Yoneyama, M]]
[[Category: Yoneyama M]]
[[Category: Ada2]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nuclear protein]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Transcriptional regulation]]
Retrieved from "https://proteopedia.org/2cuj"