5zyg: Difference between revisions

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New page: '''Unreleased structure''' The entry 5zyg is ON HOLD Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K. D...
 
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'''Unreleased structure'''


The entry 5zyg is ON HOLD
==Crystal structure of CERT START domain in complex with compound B5==
 
<StructureSection load='5zyg' size='340' side='right'caption='[[5zyg]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5zyg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZYG FirstGlance]. <br>
Description: Crystal structure of CERT START domain in complex with compound B15
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9N3:2-[4-[3-~{tert}-butyl-5-(2-pyridin-2-ylethyl)phenyl]phenyl]sulfonylethanol'>9N3</scene></td></tr>
[[Category: Kobayashi, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyg OCA], [https://pdbe.org/5zyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zyg RCSB], [https://www.ebi.ac.uk/pdbsum/5zyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyg ProSAT]</span></td></tr>
[[Category: Hanada, K]]
</table>
[[Category: Suzuki, M]]
== Disease ==
[[Category: Kumagai, K]]
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
[[Category: Sakai, S]]
== Function ==
[[Category: Nakao, N]]
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
[[Category: Egawa, D]]
== References ==
[[Category: Kawasaki, S]]
<references/>
[[Category: Hanzawa, H]]
__TOC__
[[Category: Ueno, M]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Egawa D]]
[[Category: Hanada K]]
[[Category: Hanzawa H]]
[[Category: Kawasaki S]]
[[Category: Kobayashi S]]
[[Category: Kumagai K]]
[[Category: Nakao N]]
[[Category: Sakai S]]
[[Category: Suzuki M]]
[[Category: Ueno M]]