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==Aspartate Aminotransferase Mutant MA With Isovaleric Acid==
==Aspartate Aminotransferase Mutant MA With Isovaleric Acid==
<StructureSection load='2d63' size='340' side='right' caption='[[2d63]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='2d63' size='340' side='right'caption='[[2d63]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D63 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D63 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d5y|2d5y]], [[2d61|2d61]], [[2d64|2d64]], [[2d65|2d65]], [[2d66|2d66]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aspC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d63 OCA], [https://pdbe.org/2d63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d63 RCSB], [https://www.ebi.ac.uk/pdbsum/2d63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d63 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d63 OCA], [http://pdbe.org/2d63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d63 RCSB], [http://www.ebi.ac.uk/pdbsum/2d63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2d63 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AAT_ECOLI AAT_ECOLI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Aspartate Aminotransferase|Aspartate Aminotransferase]]
*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Aspartate transaminase]]
[[Category: Large Structures]]
[[Category: Kuramitsu, S]]
[[Category: Kuramitsu S]]
[[Category: Masui, R]]
[[Category: Masui R]]
[[Category: Nakagawa, N]]
[[Category: Nakagawa N]]
[[Category: Tada, H]]
[[Category: Tada H]]
[[Category: Tanaka, Y]]
[[Category: Tanaka Y]]
[[Category: Yano, T]]
[[Category: Yano T]]
[[Category: Aspartate aminotransferase]]
[[Category: Directed evolution]]
[[Category: Protein design]]
[[Category: Protein enginnering]]
[[Category: Transferase]]

Latest revision as of 11:34, 22 May 2024

Aspartate Aminotransferase Mutant MA With Isovaleric Acid

2d63, resolution 2.05Å

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