2jkn: Difference between revisions

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==DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form)==
==DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form)==
<StructureSection load='2jkn' size='340' side='right' caption='[[2jkn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2jkn' size='340' side='right'caption='[[2jkn]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jkn]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JKN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jkn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JKN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL8:CHLORAMPHENICOL+SUCCINATE'>CL8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1usq|1usq]], [[1ut1|1ut1]], [[2jkl|2jkl]], [[2jkj|2jkj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL8:CHLORAMPHENICOL+SUCCINATE'>CL8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkn OCA], [http://pdbe.org/2jkn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jkn RCSB], [http://www.ebi.ac.uk/pdbsum/2jkn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkn OCA], [https://pdbe.org/2jkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkn RCSB], [https://www.ebi.ac.uk/pdbsum/2jkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DRAA_ECOLX DRAA_ECOLX] Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/2jkn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/2jkn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Hemagglutinin|Hemagglutinin]]
*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Davies, S G]]
[[Category: Large Structures]]
[[Category: Lea, S M]]
[[Category: Davies SG]]
[[Category: Pettigrew, D M]]
[[Category: Lea SM]]
[[Category: Roversi, P]]
[[Category: Pettigrew DM]]
[[Category: Russell, A J]]
[[Category: Roversi P]]
[[Category: Adhesin]]
[[Category: Russell AJ]]
[[Category: Cell adhesion]]
[[Category: Cell projection]]
[[Category: Chloramphenicol succinate]]
[[Category: Daec]]
[[Category: Drae]]
[[Category: Fimbrial adhesin]]
[[Category: Fimbrium]]
[[Category: Haemagglutinin]]
[[Category: Upec]]

Latest revision as of 07:57, 23 October 2024

DraE Adhesin in complex with Chloramphenicol Succinate (trigonal form)

2jkn, resolution 1.90Å

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