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==Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406==
==Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406==
<StructureSection load='2elv' size='340' side='right' caption='[[2elv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2elv' size='340' side='right'caption='[[2elv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2elv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ELV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2elv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZFAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2elv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elv OCA], [http://pdbe.org/2elv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2elv RCSB], [http://www.ebi.ac.uk/pdbsum/2elv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2elv ProSAT], [http://www.topsan.org/Proteins/RSGI/2elv TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elv OCA], [https://pdbe.org/2elv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elv RCSB], [https://www.ebi.ac.uk/pdbsum/2elv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elv ProSAT], [https://www.topsan.org/Proteins/RSGI/2elv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN]] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).  
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Harada, T]]
[[Category: Large Structures]]
[[Category: Kigawa, T]]
[[Category: Harada T]]
[[Category: Koshiba, S]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Koshiba S]]
[[Category: Tanaka, A]]
[[Category: Tanaka A]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Tomizawa, T]]
[[Category: Tomizawa T]]
[[Category: Umehara, T]]
[[Category: Umehara T]]
[[Category: Watanabe, S]]
[[Category: Watanabe S]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Yoneyama, M]]
[[Category: Yoneyama M]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Zfat zinc finger 1]]

Latest revision as of 16:35, 13 December 2023

Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406

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