6dn0: Difference between revisions
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New page: '''Unreleased structure''' The entry 6dn0 is ON HOLD Authors: Langley, D.B., Roome, B., Christ, D. Description: Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant... |
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==Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.== | |||
<StructureSection load='6dn0' size='340' side='right'caption='[[6dn0]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4x4y 4x4y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DN0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dn0 OCA], [https://pdbe.org/6dn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dn0 RCSB], [https://www.ebi.ac.uk/pdbsum/6dn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dn0 ProSAT]</span></td></tr> | |||
</table> | |||
==See Also== | |||
*[[Antibody 3D structures|Antibody 3D structures]] | |||
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |||
[[Category: | *[[3D structures of human antibody|3D structures of human antibody]] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Christ D]] | |||
[[Category: Langley DB]] | |||
[[Category: Roome B]] | |||
Latest revision as of 06:09, 11 October 2023
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
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