6gs6: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 6gs6 is ON HOLD Authors: Georgiou, C., De Simone, A., Juarez-Jimenez, J., Walkinshaw, M.D., Michel, J. Description: Cyclophilin A single mutant D66... |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Cyclophilin A single mutant D66A in complex with an inhibitor.== | |||
<StructureSection load='6gs6' size='340' side='right'caption='[[6gs6]], [[Resolution|resolution]] 1.16Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6gs6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GS6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GS6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EA4:ETHYL+N-[(4-AMINOBENZYL)CARBAMOYL]GLYCINATE'>EA4</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIA, CYPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gs6 OCA], [http://pdbe.org/6gs6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gs6 RCSB], [http://www.ebi.ac.uk/pdbsum/6gs6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gs6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Peptidylprolyl isomerase]] | |||
[[Category: Georgiou, C]] | |||
[[Category: Juarez-Jimenez, J]] | [[Category: Juarez-Jimenez, J]] | ||
[[Category: Michel, J]] | [[Category: Michel, J]] | ||
[[Category: | [[Category: Simone, A De]] | ||
[[Category: Walkinshaw, M | [[Category: Walkinshaw, M D]] | ||
[[Category: Complex]] | |||
[[Category: Cyclophilin]] | |||
[[Category: Cypa]] | |||
[[Category: Cypa mutant]] | |||
[[Category: Inhibitor]] | |||
[[Category: Isomerase]] | |||
[[Category: Ppiase]] | |||
Latest revision as of 14:28, 8 July 2020
Cyclophilin A single mutant D66A in complex with an inhibitor.
| ||||||||||||
