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==Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster.==
==Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster.==
<StructureSection load='2xhs' size='340' side='right' caption='[[2xhs]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2xhs' size='340' side='right'caption='[[2xhs]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xhs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2iz2 2iz2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XHS FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xhs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2iz2 2iz2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XHS FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ftz|1ftz]], [[2iz2|2iz2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xhs OCA], [http://pdbe.org/2xhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xhs RCSB], [http://www.ebi.ac.uk/pdbsum/2xhs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xhs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xhs OCA], [https://pdbe.org/2xhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xhs RCSB], [https://www.ebi.ac.uk/pdbsum/2xhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xhs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FTZF1_DROME FTZF1_DROME]] Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'-YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.<ref>PMID:9020363</ref> <ref>PMID:9020364</ref>  [[http://www.uniprot.org/uniprot/FTZ_DROME FTZ_DROME]] May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments.<ref>PMID:6330566</ref> <ref>PMID:2892267</ref> <ref>PMID:3049237</ref>
[https://www.uniprot.org/uniprot/FTZ_DROME FTZ_DROME] May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments.<ref>PMID:6330566</ref> <ref>PMID:2892267</ref> <ref>PMID:3049237</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Cho, H S]]
[[Category: Large Structures]]
[[Category: Yoo, J H]]
[[Category: Cho HS]]
[[Category: Transcription]]
[[Category: Yoo JH]]
Retrieved from "https://proteopedia.org/2xhs"