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==Crystal Structure of SPAP, an alkaline phosphatase from Sphingomonas showing covalent intermediate==
==Crystal Structure of SPAP, an alkaline phosphatase from Sphingomonas showing covalent intermediate==
<StructureSection load='5xwi' size='340' side='right' caption='[[5xwi]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='5xwi' size='340' side='right'caption='[[5xwi]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xwi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XWI FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xwi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingomonas_sp. Sphingomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.872&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkaline_phosphatase Alkaline phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.1 3.1.3.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwi OCA], [https://pdbe.org/5xwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwi RCSB], [https://www.ebi.ac.uk/pdbsum/5xwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwi OCA], [http://pdbe.org/5xwi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xwi RCSB], [http://www.ebi.ac.uk/pdbsum/5xwi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ALPH_SPHSX ALPH_SPHSX]] Alkaline phosphatase with broad substrate specificity. Precipitates uranium from alkaline solutions.<ref>PMID:18641147</ref> <ref>PMID:21829507</ref>
[https://www.uniprot.org/uniprot/ALPH_SPHSX ALPH_SPHSX] Alkaline phosphatase with broad substrate specificity. Precipitates uranium from alkaline solutions.<ref>PMID:18641147</ref> <ref>PMID:21829507</ref>  
 
==See Also==
*[[Alkaline phosphatase 3D structures|Alkaline phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alkaline phosphatase]]
[[Category: Large Structures]]
[[Category: Bihani, S C]]
[[Category: Sphingomonas sp]]
[[Category: Hydrolase]]
[[Category: Bihani SC]]
[[Category: Reaction intermediate]]

Latest revision as of 08:16, 22 November 2023

Crystal Structure of SPAP, an alkaline phosphatase from Sphingomonas showing covalent intermediate

5xwi, resolution 1.87Å

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