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==N-terminal domain of FACT complex subunit SPT16 from Cicer arietinum (chickpea)==
==N-terminal domain of FACT complex subunit SPT16 from Cicer arietinum (chickpea)==
<StructureSection load='5ce6' size='340' side='right' caption='[[5ce6]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5ce6' size='340' side='right'caption='[[5ce6]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ce6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cicar Cicar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CE6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ce6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cicer_arietinum Cicer arietinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CE6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LOC101489759 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3827 CICAR])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ce6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ce6 OCA], [http://pdbe.org/5ce6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ce6 RCSB], [http://www.ebi.ac.uk/pdbsum/5ce6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ce6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ce6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ce6 OCA], [https://pdbe.org/5ce6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ce6 RCSB], [https://www.ebi.ac.uk/pdbsum/5ce6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ce6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A182DWB2_CICAR A0A182DWB2_CICAR] Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.[RuleBase:RU367052]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cicar]]
[[Category: Cicer arietinum]]
[[Category: Are, V N]]
[[Category: Large Structures]]
[[Category: Ghosh, B]]
[[Category: Are VN]]
[[Category: Kumar, A]]
[[Category: Ghosh B]]
[[Category: Makde, R]]
[[Category: Kumar A]]
[[Category: Fact complex]]
[[Category: Makde R]]
[[Category: H3-h4 binding]]
[[Category: Histone chaperone]]
[[Category: Spt16]]
[[Category: Transcription]]