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==Chlamydia trachomatis LpxD with 25mM UDPGlcNAc (Complex I)==
==Chlamydia trachomatis LpxD with 25mM UDPGlcNAc (Complex I)==
<StructureSection load='2iu8' size='340' side='right' caption='[[2iu8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2iu8' size='340' side='right'caption='[[2iu8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iu8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"chlamydozoon_trachomatis"_(busacca_1935)_moshkovski_1945 "chlamydozoon trachomatis" (busacca 1935) moshkovski 1945]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IU8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iu8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydia_trachomatis Chlamydia trachomatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IU8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iu9|2iu9]], [[2iua|2iua]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu8 OCA], [http://pdbe.org/2iu8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iu8 RCSB], [http://www.ebi.ac.uk/pdbsum/2iu8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu8 OCA], [https://pdbe.org/2iu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iu8 RCSB], [https://www.ebi.ac.uk/pdbsum/2iu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LPXD_CHLTR LPXD_CHLTR] Catalyzes the N-acylation of UDP-3-O-myristoylglucosamine using 3-hydroxyarachidoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (Probable).<ref>PMID:10358025</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2iu8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2iu8" style="background-color:#fffaf0;"></div>
==See Also==
*[[UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase|UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buetow, L]]
[[Category: Chlamydia trachomatis]]
[[Category: Dawson, A]]
[[Category: Large Structures]]
[[Category: Fyffe, S]]
[[Category: Buetow L]]
[[Category: Hunter, W N]]
[[Category: Dawson A]]
[[Category: Smith, T K]]
[[Category: Fyffe S]]
[[Category: Acyltransferase]]
[[Category: Hunter WN]]
[[Category: Complex with udpglcnac]]
[[Category: Smith TK]]
[[Category: Enzyme]]
[[Category: Homotrimer]]
[[Category: Left-handed beta helix]]
[[Category: Lipid a biosynthesis]]
[[Category: Lipid synthesis]]
[[Category: Transferase]]
[[Category: Udp-3- o-acyl-glucosamine n-acyltransferase]]
Retrieved from "https://proteopedia.org/2iu8"