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==NMR solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based Gd(III)-chelate==
==NMR solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based Gd(III)-chelate==
<StructureSection load='2k62' size='340' side='right' caption='[[2k62]], [[NMR_Ensembles_of_Models | 7 NMR models]]' scene=''>
<StructureSection load='2k62' size='340' side='right'caption='[[2k62]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k62]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K62 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K62 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K62 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ITL:(3ALPHA,5ALPHA,8ALPHA)-3-[(N,N-BIS{2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}-L-GAMMA-GLUTAMYL)AMINO]CHOLAN-24-OIC+ACID'>ITL</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jn3|2jn3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ITL:(3ALPHA,5ALPHA,8ALPHA)-3-[(N,N-BIS{2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}-L-GAMMA-GLUTAMYL)AMINO]CHOLAN-24-OIC+ACID'>ITL</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k62 OCA], [https://pdbe.org/2k62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k62 RCSB], [https://www.ebi.ac.uk/pdbsum/2k62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k62 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k62 OCA], [http://pdbe.org/2k62 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k62 RCSB], [http://www.ebi.ac.uk/pdbsum/2k62 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FABPL_CHICK FABPL_CHICK]] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Binds 2 molecules of cholate per subunit.  
[https://www.uniprot.org/uniprot/FABPL_CHICK FABPL_CHICK] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Binds 2 molecules of cholate per subunit.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Fatty acid-binding protein|Fatty acid-binding protein]]
*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Aime, S]]
[[Category: Large Structures]]
[[Category: Assfalg, M]]
[[Category: Aime S]]
[[Category: Gianolio, E]]
[[Category: Assfalg M]]
[[Category: Molinari, H]]
[[Category: Gianolio E]]
[[Category: Ragona, L]]
[[Category: Molinari H]]
[[Category: Tomaselli, S]]
[[Category: Ragona L]]
[[Category: Zanzoni, S]]
[[Category: Tomaselli S]]
[[Category: Acetylation]]
[[Category: Zanzoni S]]
[[Category: Cytoplasm]]
[[Category: Haddock]]
[[Category: Hepatospecific contrast agent]]
[[Category: Lipid binding protein]]
[[Category: Lipid-binding]]
[[Category: Transport]]