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==The Crystal Structure of the Orthorhombic Form of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotin and ADP==
==The Crystal Structure of the Orthorhombic Form of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotin and ADP==
<StructureSection load='2dth' size='340' side='right' caption='[[2dth]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2dth' size='340' side='right'caption='[[2dth]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dth]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DTH FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dth]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wnl|1wnl]], [[1wpy|1wpy]], [[1wq7|1wq7]], [[1wqw|1wqw]], [[1x01|1x01]], [[2fyk|2fyk]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">birA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dth OCA], [https://pdbe.org/2dth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dth RCSB], [https://www.ebi.ac.uk/pdbsum/2dth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dth ProSAT], [https://www.topsan.org/Proteins/RSGI/2dth TOPSAN]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dth OCA], [http://pdbe.org/2dth PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dth RCSB], [http://www.ebi.ac.uk/pdbsum/2dth PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dth ProSAT], [http://www.topsan.org/Proteins/RSGI/2dth TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O57883_PYRHO O57883_PYRHO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Biotin Protein Ligase|Biotin Protein Ligase]]
*[[Biotin Protein Ligase 3D structures|Biotin Protein Ligase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrococcus horikoshii]]
[[Category: Large Structures]]
[[Category: Bagautdinov, B]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Kunishima, N]]
[[Category: Bagautdinov B]]
[[Category: Structural genomic]]
[[Category: Kunishima N]]
[[Category: Biotin biosynthesis]]
[[Category: Dimer]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]

Latest revision as of 08:29, 25 October 2023

The Crystal Structure of the Orthorhombic Form of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in Complex with Biotin and ADP

2dth, resolution 1.95Å

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