6h7n: Difference between revisions
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New page: '''Unreleased structure''' The entry 6h7n is ON HOLD Authors: Warne, T., Edwards, P.C., Dore, A.S., Leslie, A.G.W., Tate, C.G. Description: ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOU... |
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==ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9== | |||
<StructureSection load='6h7n' size='340' side='right' caption='[[6h7n]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6h7n]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama], [http://en.wikipedia.org/wiki/Ecoli Ecoli] and [http://en.wikipedia.org/wiki/Melga Melga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H7N FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=FVK:~{N}-[2-[[(2~{S})-2-oxidanyl-3-(4-oxidanylphenoxy)propyl]amino]ethyl]morpholine-4-carboxamide'>FVK</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA, fipA, tsnC, b3781, JW5856 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), ADRB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9103 MELGA])</td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h7n OCA], [http://pdbe.org/6h7n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h7n RCSB], [http://www.ebi.ac.uk/pdbsum/6h7n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h7n ProSAT]</span></td></tr> | ||
[[Category: Edwards, P | </table> | ||
[[Category: | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. [[http://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Camelus glama]] | |||
[[Category: Ecoli]] | |||
[[Category: Melga]] | |||
[[Category: Dore, A S]] | |||
[[Category: Edwards, P C]] | |||
[[Category: Leslie, A G.W]] | |||
[[Category: Tate, C G]] | |||
[[Category: Warne, T]] | [[Category: Warne, T]] | ||
[[Category: Activated]] | |||
[[Category: Beta1 adrenoceptor]] | |||
[[Category: Immune system]] | |||
[[Category: Nanobody]] | |||
[[Category: Partial agonist]] | |||
Latest revision as of 07:04, 24 October 2018
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9
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