6h7s: Difference between revisions
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New page: '''Unreleased structure''' The entry 6h7s is ON HOLD Authors: Crennell, S.J., Danson, M.J., Royer, S. Description: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L ... |
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==Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant in complex with L-2-keto-3deoxy-gluconate== | |||
<StructureSection load='6h7s' size='340' side='right'caption='[[6h7s]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6h7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H7S FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.202Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FW2:(4~{R},5~{S})-4,5,6-tris(oxidanyl)-2-oxidanylidene-hexanoic+acid'>FW2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h7s OCA], [https://pdbe.org/6h7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h7s RCSB], [https://www.ebi.ac.uk/pdbsum/6h7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h7s ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KDGA_SACSO KDGA_SACSO] Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal). It is equally active with both D- and L-glyceraldehyde.<ref>PMID:10527934</ref> <ref>PMID:12824170</ref> <ref>PMID:16330030</ref> | |||
==See Also== | |||
*[[Aldolase 3D structures|Aldolase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Crennell | __TOC__ | ||
[[Category: Danson | </StructureSection> | ||
[[Category: Royer | [[Category: Large Structures]] | ||
[[Category: Saccharolobus solfataricus]] | |||
[[Category: Crennell SJ]] | |||
[[Category: Danson MJ]] | |||
[[Category: Royer S]] | |||
Latest revision as of 06:22, 1 October 2025
Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant in complex with L-2-keto-3deoxy-gluconate
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