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| | | #REDIRECT [[6qjk]] This PDB entry is obsolete and replaced by 6qjk |
| ==Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P43==
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| <StructureSection load='5oih' size='340' side='right' caption='[[5oih]], [[Resolution|resolution]] 1.05Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[5oih]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OIH FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oih OCA], [http://pdbe.org/5oih PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oih RCSB], [http://www.ebi.ac.uk/pdbsum/5oih PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oih ProSAT]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
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| __TOC__
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| </StructureSection>
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| [[Category: Camara-Artigas, A]]
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| [[Category: Pdz domain]]
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| [[Category: Signaling protein]]
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This PDB entry is obsolete and replaced by 6qjk
