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[[Image:2oqf.jpg|left|200px]]


{{Structure
==Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A==
|PDB= 2oqf |SIZE=350|CAPTION= <scene name='initialview01'>2oqf</scene>, resolution 2.30&Aring;
<StructureSection load='2oqf' size='340' side='right'caption='[[2oqf]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=XX1:N~6~-7H-PURIN-6-YL-L-LYSINE'>XX1</scene>
<table><tr><td colspan='2'>[[2oqf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQF FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XX1:N~6~-7H-PURIN-6-YL-L-LYSINE'>XX1</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqf OCA], [https://pdbe.org/2oqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqf RCSB], [https://www.ebi.ac.uk/pdbsum/2oqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqf ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqf OCA], [http://www.ebi.ac.uk/pdbsum/2oqf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2oqf RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqf ConSurf].
<div style="clear:both"></div>


'''Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A'''
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
== References ==
==About this Structure==
<references/>
2OQF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQF OCA].
__TOC__
[[Category: Pancreatic ribonuclease]]
</StructureSection>
[[Category: Single protein]]
[[Category: Bos taurus]]
[[Category: Boerema, D J.]]
[[Category: Large Structures]]
[[Category: He, C.]]
[[Category: Boerema DJ]]
[[Category: Kent, S B.H.]]
[[Category: He C]]
[[Category: Tereshko, V A.]]
[[Category: Kent SBH]]
[[Category: Zhang, J L.]]
[[Category: Tereshko VA]]
[[Category: hydrolase]]
[[Category: Zhang JL]]
[[Category: non-natural amino acid]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:21:40 2008''

Latest revision as of 09:24, 6 November 2024

Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A

2oqf, resolution 2.30Å

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