5zb3: Difference between revisions

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==Dimeric crystal structure of ORF57 from KSHV==
==Dimeric crystal structure of ORF57 from KSHV==
<StructureSection load='5zb3' size='340' side='right' caption='[[5zb3]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
<StructureSection load='5zb3' size='340' side='right'caption='[[5zb3]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5zb3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZB3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5zb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZB3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.506&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zb1|5zb1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb3 OCA], [http://pdbe.org/5zb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zb3 RCSB], [http://www.ebi.ac.uk/pdbsum/5zb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb3 OCA], [https://pdbe.org/5zb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zb3 RCSB], [https://www.ebi.ac.uk/pdbsum/5zb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ICP27_HHV8P ICP27_HHV8P] Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular export proteins. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes.<ref>PMID:15155762</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dong, Y H]]
[[Category: Human gammaherpesvirus 8]]
[[Category: Gao, Z Q]]
[[Category: Large Structures]]
[[Category: Lan, K]]
[[Category: Dong YH]]
[[Category: Yuan, F]]
[[Category: Gao ZQ]]
[[Category: Kshv orf57]]
[[Category: Lan K]]
[[Category: Transcription]]
[[Category: Yuan F]]

Latest revision as of 10:27, 27 March 2024

Dimeric crystal structure of ORF57 from KSHV

5zb3, resolution 3.51Å

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